Kobe Bryant is out indefinitely.  From Yahoo Sports:

The Los Angeles Lakers dropped a close one to the Atlanta Hawks on Wednesday night, but might have lost much more than one game — All-Star shooting guard Kobe Bryant suffered what the team called a severe left ankle sprain late in the fourth quarter and has been ruled out indefinitely.

The injury happened in the closing seconds of the fourth quarter, with L.A. trailing the Hawks 94-92 following a very deep Bryant 3-pointer and Atlanta sharpshooter Kyle Korver going 1 for 2 at the foul line.

Bryant took the ball from Lakers point guard Steve Nash and drove right against defender Dahntay Jones, whom the Hawks recently picked up from the Dallas Mavericks. Bryant rose and faded toward the baseline to attempt a game-tying 18-foot jumper with less than six seconds left on the clock. The jumper went long and was rebounded by Korver, but before it even hit the rim, Bryant had come down and landed awkwardly with his left foot on top of Jones' right. (More on this in a second.)